Endocrine Abstracts

Introduction: Immunoglobulin-G4-related disease (IgG4RD) is a multidisciplinary problem due to plasmatic cells infiltration and areas of fibrosis in the affected tissues. In IgG4RD, elevation of serum IgG4 immunoglobulins is present. Clinically, the disease is mainly manifested as: autoimmune pancreatitis, salivary gland involvement, sclerosing cholangitis, lymphadenopathy, lachrymal gland enlargement, retroperitoneal fibrosis or orbital pseudotumor. The simultaneous involveme...

Introduction: Hypopituitarism is characterized by the absence of pituitary hormones. Depending on what pituitary hormones are missing and what is the etiology of hypopituitarism, its clinical manifestation varies. Apart from evident symptoms and signs of hypopituitarism due to hormonal insufficiencies, several studies reveal that long-standing hypopituitarism, including particularly absence of GH, is related to higher risk of metabolic syndrome.Objective...